Sister Thrift opened up a store on route 3A in Burlington (next to Abrama Pools).  Look for the bright sign on the side of the road.  They also have a thrift store in Watertown, MA.   I recently dropped off some stuff and the place is neat, clean, friendly staff and organized.  Prices are great and they sell name brand clothes too - some still with tags.  They also consigne high quality clothes.   Donations of clothing, household items, books, jewelry, videos, CDs, collectibles, etc. benefit the MetroWest Humane Society, a 501(c)(3) non-profit, no-kill animal shelter located in Ashland, and are tax deductible. 

The variety always changes as most thrift stores do and out of curiosity I was browsing around.  I was surprised to find a lot of Ann Taylor Loft shirts that were never worn for only $4.99 each!  All tops at the Burlington store are $4.99 - what a deal and you'll be surprised that it's not "homeless" looking clothes.  I found some Discovery Toys for my kids that were like new for only $3.99!  Yes quite a bargain in my eyes.  They are still looking for donations, especially kids items.  Check them out, you might find something :-)